Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011673 | 0.89 | L3MBTL1 (0.47) | ALDH1A1HPGDKDM4ETRPA1MEN1 | |
| SCHEMBL30439952 | 0.89 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ETRPA1MEN1 | |
| SCHEMBL3850258 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL8717 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL29398766 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5642419 | 0.80 | KMT2A (0.68) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL18311802 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL31106427 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL28542371 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL27670993 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039940-A | Tricyclic delta-opioid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-19 | — | — | CN | disclosed |