Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 2-Picolinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL28044625 | 0.85 | PIN1 (0.47) | L3MBTL1LMNAP4HTMELANESCN4A | |
| SCHEMBL30705003 | 0.84 | ELANE (0.48) | L3MBTL1LMNANAPRTP4HTMGRM5 | |
| Proline SCHEMBL27602067 | 0.83 | SCN4A (0.44) | ELANECHRNB2CHRNA4SCN4AHTR2C | |
| Proline SCHEMBL28485026 | 0.82 | EHMT2 (0.47) | ELANEKMT2ASCN4APOLBMAPT | |
| Quinoxaline SCHEMBL14719936 | 0.81 | ELANE (0.51) | ELANECHRNB2CHRNA4SCN4AHTR2C | |
| Quinoxaline SCHEMBL14719935 | 0.81 | ELANE (0.51) | ELANECHRNB2CHRNA4SCN4AHTR2C | |
| SCHEMBL969440 | 0.79 | CES2 (0.44) | L3MBTL1LMNANAPRTP4HTMGRM5 | |
| SCHEMBL18106842 | 0.79 | GRM5 (0.42) | L3MBTL1LMNANAPRTP4HTMGRM5 | |
| Benzoic Acid SCHEMBL31591115 | 0.79 | DAO (0.48) | NAPRTELANECES2CES1KMT2A | |
| Biphenyl SCHEMBL2308811 | 0.78 | ELANE (0.47) | LMNAELANEKMT2ASCN4AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039653-A | Solubilizing system for flavors and fragrances | FIRMENICH & CIE (CH) | 2007-09-19 | — | — | CN | claimed |