Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834011 | 0.85 | — | — | |
| Bromide SCHEMBL31683081 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL31683108 | 0.82 | — | — | |
| Iodide SCHEMBL31683076 | 0.82 | — | — | |
| Water SCHEMBL31683015 | 0.82 | — | — | |
| Adipic Acid SCHEMBL10431144 | 0.77 | BBOX1 (0.57) | FFAR3BBOX1HDAC1HDAC2 | |
| Benzoic Acid SCHEMBL31683045 | 0.74 | CA2 (0.53) | TSHRALDH1A1LMNAMAPTHTR2A | |
| SCHEMBL19409371 | 0.74 | — | — | |
| SCHEMBL12790570 | 0.73 | TSHR (0.32) | TSHRALDH1A1 | |
| Bicarbonate SCHEMBL27990882 | 0.72 | TSHR (0.50) | TSHRALDH1A1LMNAAPEX1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107868053-A | A kind of preparation method of the hydrocarbyl carbonate salt of sulfuric acid one | 深圳新宙邦科技股份有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-107868104-A | A kind of preparation method of dihydrocarbon salt | 深圳新宙邦科技股份有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-100561619-C | The preparation method of aluminium electrolytic capacitor, quaternary ammonium salt for super capacitor | SHENZHEN CAPCHEM TECHNOLOGY CO (CN) | 2009-11-18 | — | — | CN | disclosed |
| CN-101131897-A | Aluminum electrolytic capacitor, preparing method for quaternary ammonium salt for super capacitor | SHENZHEN XINYUBANG ELECTRONIC (CN) | 2008-02-27 | — | — | CN | disclosed |