Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 12/20 | 0.43 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PGC | P20142 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705650 | 0.92 | ACE (0.46) | HDAC8RENNLNFNTAFNTB | |
| SCHEMBL27705687 | 0.84 | HDAC8 (0.58) | HDAC8 | |
| SCHEMBL22962231 | 0.84 | HDAC8 (0.58) | HDAC8 | |
| SCHEMBL27705637 | 0.84 | HDAC8 (0.58) | HDAC8 | |
| SCHEMBL30839651 | 0.82 | TRHR (0.53) | RENPGCLNPEP | |
| SCHEMBL27705646 | 0.81 | HDAC8 (0.55) | HDAC8 | |
| SCHEMBL27705684 | 0.81 | TACR1 (0.56) | HDAC8 | |
| SCHEMBL27726223 | 0.81 | TACR1 (0.56) | HDAC8 | |
| SCHEMBL27726235 | 0.80 | HDAC8 (0.45) | HDAC8 | |
| SCHEMBL27726233 | 0.80 | HDAC8 (0.45) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101200493-B | (3S)-N-(L-aminoacyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, preparation method and uses thereof | UNIV CAPITAL MEDICAL | 2011-11-09 | — | — | CN | disclosed |
| CN-101200493-A | (3S)-N-(L-aminoacyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, preparation method and uses thereof | UNIV CAPITAL MEDICAL SCIENCES (CN) | 2008-06-18 | — | — | CN | disclosed |