SCHEMBL30839651

SCHEMBL30839651

COC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 1/20 0.53
▸ REN P00797 12/20 0.51
▸ KLK5 Q9Y337 1/20 0.49
▸ ACE2 Q9BYF1 1/20 0.45
▸ ACE P12821 1/20 0.44
▸ PGC P20142 1/20 0.44
▸ DPP4 P27487 1/20 0.43
▸ LNPEP Q9UIQ6 2/20 0.43
▸ F2 P00734 1/20 0.42
▸ PRSS1 P07477 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27210404 0.92 TRHR (0.54) TRHRRENACE2ACEPGC
SCHEMBL27210409 0.92 TRHR (0.54) TRHRRENACE2ACEPGC
SCHEMBL27705635 0.82 HDAC8 (0.44) RENPGCLNPEP
SCHEMBL31649400 0.82 DPP4 (0.53) TRHRRENACE2PGCDPP4
SCHEMBL30839655 0.81 DPP4 (0.66) TRHRRENDPP4
SCHEMBL7268512 0.80 KLK5 (0.69) KLK5ACEF2PRSS1
SCHEMBL12658455 0.80 KLK5 (0.69) KLK5ACEF2PRSS1
SCHEMBL28002552 0.80 KLK5 (0.69) KLK5ACEF2PRSS1
SCHEMBL28002546 0.80 KLK5 (0.69) KLK5ACEF2PRSS1
SCHEMBL16667799 0.79 KLK5 (0.58) KLK5ACEF2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594325-A1 PEG-MODIFIED CYCLIC DIPEPTIDES Novmetapharma Co., Ltd. (KR) 2025-08-06 — — EP disclosed
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-05-02 — — US disclosed
WO-2024069524-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-04-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES LNPEP, ANPEP, DNPEP TRHR 619/4885REN 821/4885KLK5 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback