Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348321 | 0.87 | AKR1C1 (0.53) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL3039302 | 0.87 | AKR1C1 (0.53) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL3039305 | 0.87 | AKR1C1 (0.53) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL30522332 | 0.78 | PTGS2 (0.55) | KMT2AMEN1ALDH1A1L3MBTL1AKR1C2 | |
| SCHEMBL6558529 | 0.76 | AKR1C1 (0.46) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4755644 | 0.74 | CES2 (0.59) | AKR1C1ALDH1A1MAPTCES2CES1 | |
| SCHEMBL6971325 | 0.74 | CES1 (0.44) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL14764079 | 0.74 | CES1 (0.48) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8041704 | 0.73 | AKR1C1 (0.50) | AKR1C1KMT2AMEN1ALDH1A1AKR1C2 | |
| SCHEMBL16246414 | 0.73 | MAPT (0.45) | AKR1C1KMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101200470-B | Cyclo c-glycosides compounds, c-glycosides intermediates as well as preparation method and uses thereof | CHINESE ACAD INST CHEMISTRY | 2010-10-13 | — | — | CN | disclosed |
| CN-101200470-A | Cyclo c-glycosides compounds, c-glycosides intermediates as well as preparation method and uses thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2008-06-18 | — | — | CN | disclosed |