Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 11/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770752 | 0.92 | NR1H4 (0.39) | NR1H4LNPEPPPARDPPARG | |
| SCHEMBL2773750 | 0.88 | NR1H4 (0.42) | NR1H4LNPEPPPARDFFAR1 | |
| SCHEMBL2773202 | 0.84 | PPARD (0.36) | NR1H4LNPEPPPARDPPARA | |
| SCHEMBL2770877 | 0.84 | NR1H4 (0.42) | NR1H4LNPEPPPARDPPARAPPARG | |
| SCHEMBL2773688 | 0.83 | NR1H4 (0.37) | NR1H4LNPEPPPARDPPARA | |
| SCHEMBL2770076 | 0.83 | NR1H4 (0.51) | NR1H4 | |
| SCHEMBL2773102 | 0.80 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL3156107 | 0.80 | NR1H4 (0.39) | NR1H4PPARDPPARA | |
| SCHEMBL2770864 | 0.80 | NR1H4 (0.39) | NR1H4LNPEPPPARD | |
| SCHEMBL16456773 | 0.79 | NR1H4 (0.58) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029547-B1 | FXR AGONISTS | LILLY CO ELI (US) | 2010-04-28 | — | — | EP | claimed |