Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 10/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944943 | 0.71 | HDAC1 (0.47) | HDAC2HDAC1IKBKETBK1LNPEP | |
| SCHEMBL5734512 | 0.68 | HPGDS (0.67) | IKBKETBK1HPGDS | |
| SCHEMBL1579012 | 0.65 | KDM4E (0.67) | HPGDS | |
| SCHEMBL222734 | 0.64 | KDM4E (0.59) | HDAC1LNPEPERAP2 | |
| SCHEMBL18379984 | 0.63 | HDAC2 (1.00) | HDAC2HDAC1HDAC3 | |
| SCHEMBL3716444 | 0.63 | KDM4E (0.63) | HDAC2HDAC1IKBKETBK1HPGDS | |
| SCHEMBL4921514 | 0.62 | HDAC1 (0.73) | HDAC2HDAC1LNPEPHDAC3 | |
| SCHEMBL2671529 | 0.62 | HDAC1 (0.58) | HDAC1LNPEPERAP2 | |
| SCHEMBL24281981 | 0.62 | KDM4E (0.57) | HDAC1LNPEPERAP2 | |
| SCHEMBL23286886 | 0.62 | LNPEP (0.45) | HDAC1LNPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061108-A | Novel 4-benzimidazol-2-ylpyridazin-3-one derivatives | AVENTIS PHARMA SA (FR) | 2007-10-24 | — | — | CN | disclosed |