Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410342 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BRIPK1MAOBGPR119 | |
| SCHEMBL16410276 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BRIPK1MAOBGPR119 | |
| SCHEMBL29805288 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BRIPK1MAOBGPR119 | |
| SCHEMBL25972059 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BRIPK1MAOBGPR119 | |
| SCHEMBL22532318 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BRORCSMN1; SMN2 | |
| SCHEMBL5335628 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1BRIPK1MAOBRORC | |
| SCHEMBL27669478 | 0.79 | GRM2 (0.43) | GPR119 | |
| Hydrochloric Acid SCHEMBL22531766 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BRORCSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29549188 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BRORCSMN1; SMN2 | |
| SCHEMBL29805596 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BRIPK1GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076330-A | Octahydropyrano [3, 4-C ] pyrroles as tachykinin receptor antagonists | MERCK & CO INC (US) | 2007-11-21 | — | — | CN | disclosed |