Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669311 | 0.88 | GRM2 (0.47) | GRM2KDM4AKCNA5RPS6KA1GPR119 | |
| SCHEMBL30487345 | 0.85 | KDM4A (0.41) | GRM2KDM4AKCNA5RPS6KA1GPR119 | |
| SCHEMBL27669339 | 0.85 | KDM4A (0.43) | KDM4AKCNA5IDO1BRD4CA12 | |
| SCHEMBL2443309 | 0.85 | GRM2 (0.44) | GRM2KDM4AKCNA5RPS6KA1GPR119 | |
| SCHEMBL29726461 | 0.85 | GRM2 (0.44) | GRM2KDM4AKCNA5RPS6KA1CTSS | |
| SCHEMBL12791296 | 0.85 | P2RX7 (0.46) | GRM2KDM4AKCNA5RPS6KA1EPHX2 | |
| SCHEMBL1654680 | 0.85 | KDM4A (0.45) | GRM2KDM4AKCNA5RPS6KA1CTSS | |
| SCHEMBL25243073 | 0.84 | MTNR1A (0.44) | GRM2KDM4AKCNA5RPS6KA1GPR119 | |
| SCHEMBL27649206 | 0.84 | CACNA1H (0.45) | KDM4AKCNA5EPHX2CACNA1HCACNA1B | |
| SCHEMBL4508520 | 0.84 | GPR119 (0.43) | GRM2KDM4AKCNA5RPS6KA1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1918124-A | New pyridin-2-one compounds useful as inhibitors of thrombin | ASTRAZENECA AB (SE) | 2007-02-21 | — | — | CN | disclosed |