Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708298 | 0.94 | TSHR (0.54) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL20796976 | 0.82 | TLR7 (0.46) | TSHRTLR7MAPTTP53GAA | |
| SCHEMBL27708262 | 0.82 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL1036042 | 0.82 | TLR7 (0.53) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL5355677 | 0.81 | MAPT (0.44) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL5797750 | 0.80 | TSHR (0.44) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL27725059 | 0.80 | TLR7 (0.42) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL5352808 | 0.80 | MAPT (0.46) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL4320463 | 0.80 | TLR7 (0.50) | TSHRMAPK1TLR7MAPTTP53 | |
| SCHEMBL8565615 | 0.80 | TSHR (0.47) | TSHRMAPK1TLR7MAPTTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014596-A | Imidazoquinolinylsulfonamides, imidazopyridinylsulfonamides, and imidazo-1, 5-naphthyridinylsulfonamides | 3M INNOVATIVE PROPERTIES CO (US) | 2007-08-08 | — | — | CN | disclosed |