Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.52 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937123 | 0.82 | HTT (0.61) | SCDDCTPP1 | |
| SCHEMBL938368 | 0.80 | SCD (0.53) | SCDDCTPP1 | |
| SCHEMBL939188 | 0.80 | HSD17B10 (0.62) | SCDDCTPP1 | |
| SCHEMBL936603 | 0.78 | SLC6A7 (0.55) | SCD | |
| SCHEMBL936620 | 0.77 | SCD (0.51) | SCDDCTPP1 | |
| SCHEMBL935839 | 0.77 | SCD (0.77) | SCDDCTPP1 | |
| SCHEMBL937326 | 0.77 | SCD (0.51) | SCDDCTPP1 | |
| SCHEMBL937862 | 0.76 | SCD (0.50) | SCDDCTPP1 | |
| SCHEMBL937239 | 0.76 | LMNA (0.55) | SCDDCTPP1 | |
| SCHEMBL936462 | 0.76 | SMN1; SMN2 (0.53) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102600162-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2012-07-25 | — | — | CN | disclosed |
| CN-101160289-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2008-04-09 | — | — | CN | disclosed |