Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697592 | 0.87 | TSHR (0.39) | TSHRALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL27508618 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL2234289 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1RECQLHPGDACACB | |
| SCHEMBL10515811 | 0.80 | EPHX1 (0.53) | TSHRALDH1A1CA1CA2ZDHHC7 | |
| SCHEMBL6523211 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1HPGD | |
| SCHEMBL6523200 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1HPGD | |
| SCHEMBL27437489 | 0.78 | CA1 (0.41) | TSHRALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL16368799 | 0.78 | KMT2A (0.41) | TSHRALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL1468764 | 0.78 | TSHR (0.43) | TSHRALDH1A1CA1CA2RECQL | |
| SCHEMBL23819235 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1CA1CA2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101151267-A | Chemical compounds | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |