Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863979 | 1.00 | REN (0.57) | RENEPHX2L3MBTL1SCN5ASCN9A | |
| SCHEMBL1863977 | 1.00 | REN (0.57) | RENEPHX2L3MBTL1SCN5ASCN9A | |
| SCHEMBL27689840 | 0.93 | REN (0.56) | REN | |
| SCHEMBL1862226 | 0.93 | REN (0.56) | REN | |
| SCHEMBL1862228 | 0.93 | REN (0.56) | REN | |
| SCHEMBL9996394 | 0.89 | REN (0.47) | REN | |
| SCHEMBL9996391 | 0.89 | REN (0.47) | REN | |
| SCHEMBL1860879 | 0.89 | REN (0.55) | REN | |
| SCHEMBL27689735 | 0.89 | REN (0.55) | REN | |
| SCHEMBL1860876 | 0.89 | REN (0.55) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101072561-B | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS INC | 2011-05-11 | — | — | CN | disclosed |
| CN-101072561-A | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS INC (US) | 2007-11-14 | — | — | CN | disclosed |