Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996391 | 1.00 | REN (0.47) | REN | |
| SCHEMBL3605969 | 0.90 | REN (0.45) | REN | |
| SCHEMBL3605975 | 0.90 | REN (0.45) | REN | |
| SCHEMBL1863977 | 0.89 | REN (0.57) | REN | |
| SCHEMBL1863979 | 0.89 | REN (0.57) | REN | |
| SCHEMBL27709552 | 0.89 | REN (0.57) | REN | |
| SCHEMBL1862228 | 0.86 | REN (0.56) | REN | |
| SCHEMBL1862226 | 0.86 | REN (0.56) | REN | |
| SCHEMBL27689840 | 0.86 | REN (0.56) | REN | |
| SCHEMBL3616993 | 0.86 | REN (0.42) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356156-B | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC | 2012-12-05 | — | — | CN | disclosed |
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |
| CN-101356156-A | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC (US) | 2009-01-28 | — | — | CN | disclosed |