Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335756 | 0.84 | RXFP1 (0.56) | KDM4ECASP3CASP7CASP9PTGDR2 | |
| SCHEMBL31520212 | 0.83 | TSHR (0.67) | F9TSHRKDM4ECASP3CASP7 | |
| SCHEMBL11490448 | 0.83 | TSHR (0.67) | F9TSHRKDM4ECASP3CASP7 | |
| SCHEMBL22534435 | 0.82 | F9 (0.53) | F9TSHRKDM4ECASP3CASP7 | |
| SCHEMBL6579486 | 0.82 | NCEH1 (0.55) | TSHRKDM4ECASP3CASP7CASP9 | |
| SCHEMBL16559854 | 0.79 | ALDH1A1 (0.55) | TSHRKDM4ECASP3CASP7CASP9 | |
| SCHEMBL4517104 | 0.77 | MEN1 (0.57) | TSHRKDM4ECASP3PTGDR2POLB | |
| SCHEMBL6999173 | 0.76 | PDE10A (0.50) | F9TSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL12611682 | 0.76 | GAA (0.55) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL27642138 | 0.76 | ALDH1A1 (0.52) | TSHRKDM4EPTGDR2POLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101056635-A | Niacin receptor agonists, compositions containing such compounds and methods of treatment | MERCK & CO INC (US) | 2007-10-17 | — | — | CN | disclosed |