Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27710784 | 0.81 | TPMT (0.40) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL23279535 | 0.80 | KDM4E (0.49) | CYP4A11CYP4F2LMNAHPGDKDM4E | |
| SCHEMBL27389337 | 0.80 | RARB (0.41) | ALDH1A1 | |
| SCHEMBL16749775 | 0.79 | CA12 (0.56) | CYP4A11CYP4F2LMNAHPGDKDM4E | |
| SCHEMBL9121827 | 0.79 | CA12 (0.60) | LMNAKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL7234945 | 0.79 | CA12 (0.60) | LMNAKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL475791 | 0.78 | SLC7A5 (0.49) | CYP4A11CYP4F2LMNAHPGDKDM4E | |
| SCHEMBL16247137 | 0.78 | CYP4A11 (0.51) | CYP4A11CYP4F2LMNAHPGDKDM4E | |
| Methyl Alcohol SCHEMBL28269742 | 0.77 | CA12 (0.58) | LMNAKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL8758786 | 0.77 | CYP4A11 (0.72) | CYP4A11CYP4F2HPGDALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201740-C | Medicine for treating intermittent claudication containing pyrroloazepine * compound | DAIICHI SUNTORY LTD (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1297351-A | Medicine for treating intermittent claudication containing pyrroloazepine * compound | SUNTORY LTD (JP) | 2001-05-30 | — | — | CN | disclosed |