SCHEMBL27710909

SCHEMBL27710909

CC[C@H](CCO)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 6/20 0.50
LMNA P02545 1/20 0.50
CCR5 P51681 1/20 0.42
HKDC1 Q2TB90 1/20 0.40
AOC3 Q16853 2/20 0.39
NOS3 P29474 1/20 0.39
NOS2 P35228 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
GABBR2 O75899 1/20 0.38
GABBR1 Q9UBS5 1/20 0.38
RIPK1 Q13546 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18793698 1.00 TRPA1 (0.50) TRPA1LMNACCR5HKDC1AOC3
SCHEMBL1144424 1.00 TRPA1 (0.50) TRPA1LMNACCR5HKDC1AOC3
SCHEMBL1144368 0.88 LMNA (0.47) TRPA1LMNACCR5HKDC1AOC3
SCHEMBL1308070 0.86 TRPA1 (0.52) TRPA1LMNAGABBR2GABBR1RIPK1
SCHEMBL16057545 0.86 LMNA (0.45) TRPA1LMNACCR5HKDC1
SCHEMBL1144478 0.85 TRPA1 (0.48) TRPA1LMNAAOC3ESR1ESR2
Hydrogen Peroxide SCHEMBL11212534 0.84 LMNA (0.52) TRPA1LMNACCR5HKDC1AOC3
SCHEMBL17264999 0.83 TRPA1 (0.56) TRPA1LMNAHKDC1AOC3NOS3
SCHEMBL233438 0.82 LMNA (0.48) LMNACCR5HKDC1AOC3ESR1
SCHEMBL502934 0.82 LMNA (0.54) TRPA1LMNACCR5HKDC1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101020665-A Gamma-aryl substituted chiral triazole bactericides and their synthesis process UNIV CENTRAL CHINA NORMAL (CN) 2007-08-22 CN disclosed