SCHEMBL27710993

SCHEMBL27710993

CC(C)Cl.CC(C)OC=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293 0.93
SCHEMBL30154499 0.93 TDP1 (0.30)
SCHEMBL14637528 0.90
SCHEMBL29119755 0.90
Ammonia Solution, Strong SCHEMBL28600190 0.90
Cyclooctane SCHEMBL11798106 0.84 ADH1B (0.32)
Cyclopropane SCHEMBL11789277 0.84
Cyclopentane SCHEMBL11787886 0.84 ADH1B (0.32)
Isopropyl Alcohol SCHEMBL2441841 0.84 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL227420 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101830899-A Heterocyclic carbamate derivatives, their manufacture and use as pharmaceutical agents HOFFMANN LA ROCHE 2010-09-15 CN disclosed
CN-101087786-A Heterocyclic carbamate derivatives, their preparation and use as pharmaceutical agents HOFFMANN LA ROCHE (CH) 2007-12-12 CN disclosed