Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731712 | 0.83 | WDR5 (0.47) | ABL1MTORGSK3BGSK3AMAPT | |
| SCHEMBL3700050 | 0.83 | MTOR (0.41) | ABL1MTORKDM4EFASNROCK2 | |
| SCHEMBL3707626 | 0.81 | FASN (0.38) | ABL1MTORGSK3BGSK3AFASN | |
| SCHEMBL24424559 | 0.81 | KDM4E (0.52) | KDM4EMAPTROCK2LMNAALDH1A1 | |
| SCHEMBL3699072 | 0.76 | BRD4 (0.40) | FASNROCK2EPHX2TRPV1CREBBP | |
| SCHEMBL3701259 | 0.75 | FASN (0.42) | FASN | |
| SCHEMBL24423574 | 0.74 | DYRK1A (0.44) | ABL1KDM4EGSK3BMAPTROCK2 | |
| SCHEMBL3700861 | 0.74 | FASN (0.42) | FASN | |
| SCHEMBL6730692 | 0.74 | FASN (0.42) | ABL1KDM4EFASNDYRK1A | |
| SCHEMBL3692104 | 0.73 | TP53 (0.45) | FASNDYRK1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242819-A | Hypnotics and combinations of substituted biaryl and heteroaryl compounds and therapeutic uses thereof | AVENTIS PHARMA INC (US) | 2008-08-13 | — | — | CN | disclosed |