Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731819 | 0.94 | ALDH1A1 (0.44) | SMN1; SMN2LMNATDP1L3MBTL1KDM4E | |
| SCHEMBL27731727 | 0.91 | ALDH1A1 (0.47) | SMN1; SMN2HTTLMNATDP1L3MBTL1 | |
| SCHEMBL27731737 | 0.88 | CYP2C9 (0.43) | SMN1; SMN2HTTLMNATDP1L3MBTL1 | |
| SCHEMBL27711281 | 0.86 | KDM4E (0.46) | HTTKDM4EASPHRIOX2KDM8 | |
| SCHEMBL27711256 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTLMNATDP1L3MBTL1 | |
| SCHEMBL9674445 | 0.84 | AKR1C3 (0.49) | SMN1; SMN2LMNATDP1KDM4EASPH | |
| SCHEMBL27731790 | 0.82 | CISD1 (0.42) | SMN1; SMN2KDM4EASPHRIOX2KDM8 | |
| SCHEMBL27711241 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2HTTLMNATDP1L3MBTL1 | |
| SCHEMBL27731740 | 0.82 | PPARA (0.53) | SMN1; SMN2HTTKDM4EASPHRIOX2 | |
| SCHEMBL27711287 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2LMNATDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |