Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 2/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.47 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RNF4 | P78317 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293470 | 1.00 | YAP1 (0.47) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2296303 | 1.00 | YAP1 (0.47) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2296532 | 0.89 | MEN1 (0.40) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2299149 | 0.89 | MEN1 (0.40) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2297338 | 0.88 | YAP1 (0.44) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL27731732 | 0.88 | YAP1 (0.44) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2298889 | 0.88 | YAP1 (0.44) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2297810 | 0.86 | YAP1 (0.43) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL2298495 | 0.86 | YAP1 (0.43) | YAP1TEAD4TEAD2ALDH1A1MEN1 | |
| SCHEMBL27711284 | 0.83 | ALOX5 (0.49) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |