Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502520 | 0.92 | MAPT (0.41) | GSTP1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10802875 | 0.84 | MAPT (0.37) | GSTP1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL11883529 | 0.84 | TYMP (0.40) | GSTP1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL2490095 | 0.80 | GSTP1 (0.32) | GSTP1ALDH1A1CYP3A4 | |
| SCHEMBL9764177 | 0.78 | HIF1A (0.31) | HIF1A | |
| SCHEMBL8893889 | 0.77 | ALOX15 (0.34) | GSTP1MEN1KMT2AALOX15 | |
| SCHEMBL1719496 | 0.76 | — | — | |
| SCHEMBL25365091 | 0.74 | — | — | |
| SCHEMBL11248818 | 0.74 | — | — | |
| SCHEMBL15133421 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097925-B1 | NOVEL BENZOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO (JP) | 2006-09-13 | — | — | EP | claimed |
| US-6756497-B1 | REACTING SUBSTITUTED BICYCLOHEPTENONE WITH ALKALI METAL ALKOXIDE OR ALKALI METAL OR ALKALINE EARTH METAL HYDROXIDE AND WATER OR METHANOL, ETHANOL, PROPANOL, ISOPROPANOL, BUTANOL OR TERT-BUTANOL IN LISTED ALCOHOLS OR TETRAHYDROFURAN AS SOLVENT | NIPPON SODA CO., LTD. (JP) | 2004-06-29 | — | — | US | claimed |
| EP-1097925-A1 | NOVEL BENZOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO., LTD. (JP) | 2001-05-09 | — | — | EP | claimed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | claimed |
| US-8632759-B2 | Hair restorer | COSMO OIL CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120122974-A1 | HAIR RESTORER | COSMO OIL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-8133479-B2 | Hair restorer | COSMO OIL CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20090182033-A1 | Cyclic Amine Derivatives and Their Uses | ARGENTA DISCOVERY LTD. (GB) | 2009-07-16 | — | — | US | disclosed |
| EP-1971572-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USES | Argenta Discovery Limited (GB) | 2008-09-24 | — | — | EP | disclosed |
| US-20070249721-A1 | Hair Restorer | COSMO ALA CO., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| WO-2007068929-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2007-06-21 | — | — | WO | disclosed |
| EP-1097925-B1 | NOVEL BENZOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| EP-0074856-A3 | RESOLUTION OF RACEMIC BICYCLOHEPTENONES | GLAXO GROUP LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| EP-0074856-A3 | RESOLUTION OF RACEMIC BICYCLOHEPTENONES | GLAXO GROUP LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| EP-0074856-A2 | Resolution of racemic bicycloheptenones | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| US-3899678-A | Radiation sensitive marking and process utilizing same | BELL TELEPHONE LABOR INC | 1975-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182033-A1 | Cyclic Amine Derivatives and Their Uses | CHRM2, CHRM3, CHRM1 | GSTP1 3261/4885HDAC4 1901/4885HDAC2 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.