Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277115 | 0.78 | GSTP1 (0.37) | HIF1A | |
| SCHEMBL11502520 | 0.71 | MAPT (0.41) | HIF1A | |
| SCHEMBL11883529 | 0.69 | TYMP (0.40) | HIF1A | |
| SCHEMBL2490095 | 0.66 | GSTP1 (0.32) | — | |
| SCHEMBL10802875 | 0.65 | MAPT (0.37) | HIF1A | |
| SCHEMBL6244929 | 0.64 | GSTP1 (0.38) | HIF1A | |
| SCHEMBL6244920 | 0.64 | GSTP1 (0.38) | HIF1A | |
| SCHEMBL6244923 | 0.64 | GSTP1 (0.38) | HIF1A | |
| SCHEMBL354995 | 0.64 | GSTP1 (0.38) | HIF1A | |
| SCHEMBL18198950 | 0.64 | GSTP1 (0.38) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255307-B1 | PROCESS FOR THE SYNTHESIS OF PENEMS | PFIZER INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4782146-A | FROM AZETIDINONES VIA 1-AZA-4,5-DITHIABICYCLO(4.2.0)OCT-2-EN-8-ONE-2-CARBOXYLATES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0255307-A1 | Process for the synthesis of penems | PFIZER INC. (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4695626-A | 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters | PFIZER INC. (US) | 1987-09-22 | — | — | US | disclosed |