Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913887 | 0.85 | HSP90AB1 (0.40) | TAS2R14LMNAGAAPDK2CTNNB1 | |
| SCHEMBL29410857 | 0.82 | CTNNB1 (0.57) | LMNAGAAPDK2CTNNB1WNT3A | |
| SCHEMBL1950901 | 0.82 | CTNNB1 (0.57) | LMNAGAAPDK2CTNNB1WNT3A | |
| SCHEMBL24450817 | 0.81 | PDK2 (0.44) | TAS2R14LMNAGAAPDK2CTNNB1 | |
| SCHEMBL4873112 | 0.81 | CTSS (0.55) | TAS2R14LMNAGAAPDK2CTNNB1 | |
| SCHEMBL28798676 | 0.81 | CTSS (0.55) | TAS2R14LMNAGAAPDK2CTNNB1 | |
| Hydrochloric Acid SCHEMBL5819908 | 0.81 | CTNNB1 (0.55) | LMNAGAAPDK2CTNNB1WNT3A | |
| SCHEMBL31693161 | 0.81 | TAS2R14 (0.53) | TAS2R14LMNAGAAPDK2SMN1; SMN2 | |
| SCHEMBL2473776 | 0.81 | TAS2R14 (0.53) | TAS2R14LMNAGAAPDK2SMN1; SMN2 | |
| SCHEMBL4104026 | 0.80 | CTNNB1 (0.43) | TAS2R14LMNAGAAPDK2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307852-A | Cyclic amine compounds | DAIICHI SANKYO CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-102307847-A | Indanyl compounds | DAIICHI SANKYO CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-102112475-A | Imidazopyridine and related analogs as sirtuin modulators | SIRTRIS PHARMACEUTICALS INC | 2011-06-29 | — | — | CN | disclosed |
| CN-102083821-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-06-01 | — | — | CN | disclosed |
| CN-102056907-A | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-11 | — | — | CN | disclosed |
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |