Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712337 | 0.87 | IDO1 (0.37) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL27692521 | 0.81 | CTSL (0.55) | RAB9ACTSLCTSKMAPTNPC1 | |
| SCHEMBL5196554 | 0.79 | PYGL (0.46) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL5192234 | 0.79 | PYGL (0.46) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL5194411 | 0.79 | PYGL (0.46) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL5197354 | 0.79 | PYGL (0.46) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL5196425 | 0.78 | PYGL (0.45) | IDO1PYGLCYP2C9RAB9AL3MBTL1 | |
| SCHEMBL5193270 | 0.77 | PYGL (0.56) | IDO1PYGLCYP2C9CTSLCTSK | |
| SCHEMBL27712399 | 0.77 | PYGL (0.56) | IDO1PYGLCYP2C9CTSLCTSK | |
| SCHEMBL27712418 | 0.76 | IDO1 (0.40) | IDO1PYGLCYP2C9RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101098852-A | Glycogen phosphorylase inhibitor compounds and pharmaceutical compositions thereof | SMITHKLINE BEECHAM CORP (US) | 2008-01-02 | — | — | CN | disclosed |