Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797072 | 0.89 | S1PR1 (0.60) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL4289421 | 0.89 | S1PR1 (0.60) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL4300178 | 0.89 | S1PR1 (0.60) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL4298783 | 0.89 | S1PR1 (0.60) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL28766861 | 0.86 | SPHK1 (0.55) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL27692855 | 0.84 | SIGMAR1 (0.49) | S1PR1THRATHRBS1PR3S1PR4 | |
| SCHEMBL4287254 | 0.80 | S1PR1 (0.53) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL4286810 | 0.79 | S1PR1 (0.52) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL4300481 | 0.79 | LMNA (0.53) | S1PR1S1PR3S1PR4S1PR5ALDH1A1 | |
| SCHEMBL4293954 | 0.78 | S1PR1 (0.63) | S1PR1THRATHRBS1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107218-A | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-01-16 | — | — | CN | disclosed |