Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712766 | 0.80 | SRD5A1 (0.31) | — | |
| SCHEMBL27693033 | 0.78 | S100B (0.35) | HPGD | |
| SCHEMBL27693209 | 0.70 | HSD17B10 (0.39) | HPGDCHRM2CHRM4CHRM1SLC6A7 | |
| SCHEMBL20062932 | 0.69 | SLC6A7 (0.35) | SLC6A7SCN9A | |
| SCHEMBL28770763 | 0.65 | ROCK1 (0.55) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9959879 | 0.65 | HPGD (0.53) | HPGD | |
| SCHEMBL6024373 | 0.63 | SMN1; SMN2 (0.47) | HPGD | |
| SCHEMBL2340654 | 0.62 | HPGD (0.57) | HPGD | |
| SCHEMBL20071765 | 0.61 | SLC6A7 (0.34) | SLC6A7SCN9A | |
| SCHEMBL8135114 | 0.60 | NOTUM (0.34) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103019-A | 2- (Cyclic aminocarbonyl) indoline derivative and pharmaceutical composition containing same | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-01-09 | — | — | CN | disclosed |