Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712868 | 0.92 | KMT2A (0.56) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL27712950 | 0.86 | KMT2A (0.50) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL27733287 | 0.81 | FNTA (0.51) | MAPTPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27809585 | 0.79 | KMT2A (0.39) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL27733288 | 0.72 | FNTA (0.57) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL27966202 | 0.71 | MEN1 (0.71) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL27818037 | 0.71 | FNTA (0.56) | MAPTPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4167790 | 0.69 | CNR1 (0.60) | MAPTPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27809584 | 0.69 | HTR1A (0.40) | MAPTPOLBKDM4EKMT2AMEN1 | |
| SCHEMBL28784460 | 0.67 | SMN1; SMN2 (0.36) | MAPTKMT2AMEN1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250134-B | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN | 2011-07-20 | — | — | CN | claimed |
| CN-101250134-A | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN (CN) | 2008-08-27 | — | — | CN | claimed |