Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712950 | 0.94 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27712867 | 0.92 | MAPT (0.48) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27733288 | 0.78 | FNTA (0.57) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27818037 | 0.77 | FNTA (0.56) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27809584 | 0.75 | HTR1A (0.40) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27733289 | 0.73 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27733287 | 0.71 | FNTA (0.51) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27809586 | 0.70 | TDP1 (0.40) | KMT2AMEN1SMN1; SMN2MAPTTP53 | |
| SCHEMBL27713011 | 0.69 | MEN1 (0.57) | KMT2AMEN1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL12197936 | 0.69 | PTPN1 (0.73) | KMT2AMEN1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250134-B | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN | 2011-07-20 | — | — | CN | claimed |
| CN-101250134-A | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN (CN) | 2008-08-27 | — | — | CN | claimed |