Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234652 | 0.87 | ADRA2A (0.45) | KMT2AADRA2AADRA2BADRA2CP2RX7 | |
| SCHEMBL28841573 | 0.83 | ADRA2A (0.47) | KMT2AADRA2AADRA2BADRA2CP2RX7 | |
| SCHEMBL2873658 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL15157057 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1576332 | 0.80 | KMT2A (0.56) | KMT2AADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL16234638 | 0.78 | P2RX7 (0.44) | KMT2AADRA2AADRA2BADRA2CP2RX7 | |
| SCHEMBL2873280 | 0.78 | KMT2A (0.53) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL11081014 | 0.77 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CP2RX7ALDH1A1 | |
| SCHEMBL2872955 | 0.76 | KMT2A (0.51) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2040320 | 0.76 | P2RX7 (0.48) | ADRA2AADRA2BADRA2CP2RX7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101040037-B | Organic compounds | GIVAUDAN SA | 2010-08-18 | — | — | CN | claimed |
| CN-101040037-A | Organic compounds | GIVAUDAN SA (CH) | 2007-09-19 | — | — | CN | claimed |