Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102165 | 0.95 | PTGDR2 (0.70) | PTGDR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL9975978 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1MAPTHTTTDP1 | |
| SCHEMBL1714590 | 0.82 | PTGDR2 (0.68) | PTGDR2KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL28770778 | 0.82 | PTGDR2 (0.69) | PTGDR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL1714744 | 0.82 | LMNA (0.81) | KDM4EALDH1A1MAPTHTTTDP1 | |
| SCHEMBL27712886 | 0.81 | PTGDR2 (0.71) | PTGDR2SMN1; SMN2L3MBTL1MEN1ALOX15 | |
| SCHEMBL13800181 | 0.81 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1TP53 | |
| SCHEMBL27693395 | 0.81 | PTGDR2 (0.71) | PTGDR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL27712976 | 0.81 | PTGDR2 (0.71) | PTGDR2KDM4EALDH1A1MAPTHTT | |
| SCHEMBL27712890 | 0.81 | PTGDR2 (0.71) | PTGDR2SMN1; SMN2L3MBTL1MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107226-A | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | CN | disclosed |