Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713450 | 0.85 | HRH3 (0.44) | HRH3PDGFRBPDGFRARAB9AALDH1A1 | |
| SCHEMBL27733721 | 0.78 | KDM4E (0.47) | TSHRPDGFRBPDGFRARAB9AALDH1A1 | |
| SCHEMBL27713360 | 0.78 | FLT3 (0.45) | MEN1KMT2ACYP1A2CYP2C9HRH3 | |
| SCHEMBL3525164 | 0.78 | CYP1A2 (0.46) | ELANEMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11764648 | 0.78 | CTSV (0.47) | MEN1KMT2ACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL27713342 | 0.75 | HRH4 (0.44) | MEN1KMT2APDGFRBPDGFRARAB9A | |
| SCHEMBL10102373 | 0.73 | GRM1 (0.55) | MEN1KMT2ACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL27733691 | 0.72 | ELANE (0.41) | ELANEMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL24553587 | 0.72 | TSHR (0.60) | MEN1KMT2ACYP1A2CYP2C9CYP3A4 | |
| SCHEMBL27281372 | 0.71 | RAB9A (0.56) | MEN1KMT2ACYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |