Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8279432 | 0.71 | CREBBP (0.50) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL8582807 | 0.71 | IDO1 (0.40) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL338205 | 0.70 | IDO1 (0.57) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL16181708 | 0.70 | IDO1 (0.57) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL16711400 | 0.70 | IDO1 (0.57) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL12661831 | 0.70 | IDO1 (0.57) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL27406608 | 0.68 | IDO1 (0.38) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL14048753 | 0.65 | MEN1 (0.56) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL12571712 | 0.65 | IDO1 (0.52) | IDO1MEN1KMT2ANPC1GAA | |
| SCHEMBL12334112 | 0.65 | HTR5A (0.32) | MEN1KMT2AGAAALOX12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101092405-B | Derivative of new benzothiadiazines, preparation method and usage | THADWEIK ACADEMY OF MEDICINE BEIJING | 2010-05-12 | — | — | CN | disclosed |
| CN-101092405-A | Derivative of new benzothiadiazines, preparation method and usage | ENHUA MEDICINES INST BEIJING (CN) | 2007-12-26 | — | — | CN | disclosed |