Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138740 | 0.82 | AR (0.43) | ARTSHRDYRK1AALDH1A1TTR | |
| SCHEMBL17570551 | 0.81 | TSHR (0.42) | ARTSHRGRM6ALDH1A1HPGD | |
| SCHEMBL29331537 | 0.80 | ALDH1A1 (0.35) | TSHRGRM6ALDH1A1HPGDHTT | |
| SCHEMBL29398131 | 0.77 | TSHR (0.44) | ARTSHRGRM6ALDH1A1HPGD | |
| SCHEMBL8852021 | 0.77 | TSHR (0.44) | ARTSHRGRM6ALDH1A1HPGD | |
| SCHEMBL24196688 | 0.75 | ALDH1A1 (0.36) | TSHRDYRK1AALDH1A1HPGDTTR | |
| SCHEMBL1585098 | 0.75 | AR (0.52) | ARTSHRALDH1A1NISCHCYP2A6 | |
| SCHEMBL6982992 | 0.74 | AR (0.37) | ARTSHRGRM6ALDH1A1HPGD | |
| SCHEMBL9575173 | 0.74 | GRM6 (0.41) | ARTSHRGRM6ALDH1A1HTT | |
| SCHEMBL16122042 | 0.74 | TRPV4 (0.41) | ARTSHRGRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101184760-A | Heterocyclic spiro-compounds | SPEEDEL EXPERIMENTA AG (CH) | 2008-05-21 | — | — | CN | disclosed |