Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31528743 | 0.86 | MMP1 (0.73) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL11707124 | 0.86 | MMP1 (0.73) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL11707129 | 0.86 | MMP1 (0.73) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL30669841 | 0.86 | HDAC2 (0.68) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL5599044 | 0.81 | F3 (0.86) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL5599042 | 0.81 | F3 (0.86) | MMP1MMP2MMP9EGFRHDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL28105146 | 0.81 | THRB (0.89) | MMP1MMP2MMP9EGFRHDAC3 | |
| SCHEMBL23295211 | 0.81 | MAPT (0.85) | MMP1MMP2MMP9EGFRMAPT | |
| N-(4-Methoxyphenyl)Cinnamamide SCHEMBL4131112 | 0.81 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL21616500 | 0.81 | MAPT (0.85) | MMP1MMP2MMP9EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101274901-B | Synthetic method for (E)-3-aryl-2-acrylic amide compound | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | disclosed |
| CN-101274901-A | Synthetic method for (E)-3-aryl-2-acrylic amide compound | UNIV ZHEJIANG (CN) | 2008-10-01 | — | — | CN | disclosed |