Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894379 | 0.80 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27825846 | 0.76 | CAPN1 (0.42) | CAPN1 | |
| Ethoxycarbonyl Group SCHEMBL27908382 | 0.74 | TRPM8 (0.36) | CAPN1 | |
| SCHEMBL26583 | 0.71 | CA1 (0.48) | — | |
| Benzene SCHEMBL28219713 | 0.71 | CA1 (0.48) | — | |
| SCHEMBL9548874 | 0.71 | CAPN1 (0.43) | CAPN1 | |
| SCHEMBL7455002 | 0.70 | CAPN1 (0.43) | CAPN1 | |
| SCHEMBL2007361 | 0.70 | — | — | |
| SCHEMBL2754650 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL27697032 | 0.69 | CA1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104341395-A | Novel azole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-02-11 | — | — | CN | disclosed |
| CN-103732059-A | Nuclear hormone receptor modulators | ABBOTT LAB | 2014-04-16 | — | — | CN | disclosed |
| CN-1993361-B | Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER PHARMACEUTICALS CORP | 2010-05-26 | — | — | CN | disclosed |
| CN-101460497-A | Pyrrolopyridine and thiazolopyridine compounds as HIF modulators | FIBROGEN INC (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101277962-A | Bicyclic aromatic compounds useful as inhibitors of mitogen-activated protein kinase-activated protein kinase-2 | NOVARTIS PHARMA AG (CH) | 2008-10-01 | — | — | CN | disclosed |