Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258334 | 0.78 | CA2 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6589802 | 0.73 | CA1 (0.66) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9548874 | 0.72 | CAPN1 (0.43) | CAPN1KDM4EALDH1A1TRPM8CYP1A2 | |
| SCHEMBL13527822 | 0.72 | CA2 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6991225 | 0.72 | CA1 (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL17891745 | 0.72 | CA2 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| Ammonia Solution, Strong SCHEMBL28745712 | 0.72 | CA1 (0.63) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1779057 | 0.71 | NOS2 (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL21352238 | 0.71 | CAPN1 (0.51) | CAPN1ALDH1A1TSHRTRPM8 | |
| SCHEMBL980388 | 0.70 | CA1 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-B1 | 5-HT1F agonists for the treatment of migraine | LILLY CO ELI (US) | 2002-12-11 | — | — | EP | disclosed |
| US-5721252-A | PIPERIDINYL-1H-INDOLE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| US-5521196-A | ANALGESICS USING SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |