Sugi Predict

Sugi Predict / Compounds / SCHEMBL27715656

SCHEMBL27715656

SCHEMBL27715656

COc1cccc(-c2cccc3sc(C(=O)CS(=O)(=O)ONC(=N)N)cc23)c1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC9A1 P19634 18/20 0.62
▸ F9 P00740 2/20 0.44
▸ F10 P00742 1/20 0.41
▸ PLAU P00749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3813474 0.89 F9 (0.57) SLC9A1F9
SCHEMBL27695569 0.88 SLC9A1 (0.58) SLC9A1F9
SCHEMBL27695585 0.88 SLC9A1 (0.57) SLC9A1F9
SCHEMBL27715467 0.87 SLC9A1 (0.46) SLC9A1F9
SCHEMBL27695553 0.86 SLC9A1 (0.47) SLC9A1F9F10PLAU
SCHEMBL28767338 0.85 SLC9A1 (0.56) SLC9A1F9
SCHEMBL27715549 0.85 SLC9A1 (0.47) SLC9A1F9
SCHEMBL27715654 0.85 F9 (0.46) SLC9A1F9
SCHEMBL3815060 0.84 SLC9A1 (0.56) SLC9A1F9F10PLAU
SCHEMBL27715652 0.83 SLC9A1 (0.44) SLC9A1F9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101137641-B Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same KOREA RES INST CHEM TECH 2010-11-24 — — CN disclosed
CN-101137641-A Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same KOREA RES INST CHEM TECH (KR) 2008-03-05 — — CN disclosed