Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RBP4 | P02753 | 4/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737070 | 0.81 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL27737057 | 0.80 | NAMPT (0.42) | — | |
| SCHEMBL615642 | 0.80 | AVPR1A (0.53) | NPSR1RBP4HSD11B1TRPA1TRPV1 | |
| SCHEMBL613046 | 0.80 | RBP4 (0.51) | NPSR1RBP4HSD11B1TRPA1TRPV1 | |
| SCHEMBL615807 | 0.76 | AVPR1A (0.63) | NPSR1RBP4HSD11B1TRPA1TRPV1 | |
| SCHEMBL16690842 | 0.75 | RBP4 (0.72) | NPSR1RBP4HSD11B1TRPA1TRPV1 | |
| SCHEMBL16689591 | 0.74 | HSD11B1 (0.59) | NPSR1RBP4HSD11B1TRPA1TRPV1 | |
| SCHEMBL28775555 | 0.73 | F10 (0.40) | — | |
| SCHEMBL5457598 | 0.69 | HDAC2 (0.45) | — | |
| SCHEMBL12024747 | 0.68 | KRAS (0.51) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277945-A | Indol-3-yl-carbonyl-piperidine and piperazine derivatives | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |