SCHEMBL27716634

SCHEMBL27716634

NCc1c(Cl)cccc1-c1ccc(C(=O)O)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 6/20 0.53
PRSS12 P56730 1/20 0.51
SUCNR1 Q9BXA5 2/20 0.48
SERPINE1 P05121 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPT P10636 3/20 0.48
GRIK1 P39086 2/20 0.48
PKM P14618 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HDAC1 Q13547 1/20 0.46
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
DHODH Q02127 1/20 0.45
F11 P03951 1/20 0.44
ALDH1A1 P00352 1/20 0.44
ABL1 P00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275464 0.86 PRSS12 (0.65) ACLYPRSS12SUCNR1SERPINE1MEN1
SCHEMBL2273555 0.85 ACLY (0.58) ACLYPRSS12SUCNR1SERPINE1MEN1
SCHEMBL2267843 0.83 ACLY (0.56) ACLYPRSS12SUCNR1SERPINE1MEN1
SCHEMBL2270919 0.83 ACLY (0.56) ACLYPRSS12SUCNR1SERPINE1MEN1
SCHEMBL27696788 0.81 ACLY (0.59) ACLYSUCNR1SERPINE1MEN1KMT2A
SCHEMBL27696818 0.80 SERPINE1 (0.57) ACLYSUCNR1SERPINE1MEN1KMT2A
SCHEMBL27716606 0.80 HDAC1 (0.69) ACLYSUCNR1MEN1KMT2AMAPT
SCHEMBL27716665 0.78 HDAC1 (0.62) ACLYSUCNR1MEN1KMT2AMAPT
SCHEMBL5146969 0.78 SERPINE1 (0.63) ACLYPRSS12SUCNR1SERPINE1MEN1
SCHEMBL2272873 0.78 SERPINE1 (0.63) ACLYPRSS12SUCNR1SERPINE1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-B novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed