Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854529 | 0.82 | HTR6 (0.48) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3853341 | 0.82 | HTR6 (0.50) | HTR6HTR1ADRD2HTR2AHTR7 | |
| Tert-Butyl Formate SCHEMBL27716656 | 0.80 | HTR6 (0.43) | HTR6NPY2RHTR1ADRD2HTR2A | |
| Tert-Butyl Formate SCHEMBL27716668 | 0.79 | HTR6 (0.46) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL27716667 | 0.78 | NPY2R (0.42) | HTR6NPY2RHTR1ADRD2HTR7 | |
| SCHEMBL1136500 | 0.74 | HTR6 (0.50) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3853259 | 0.73 | GPR119 (0.47) | NPY2RDRD2KMT2AMEN1TP53 | |
| SCHEMBL3852196 | 0.73 | GPR119 (0.47) | NPY2RKMT2AMEN1TP53 | |
| SCHEMBL1136462 | 0.72 | HTR6 (0.47) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL1136498 | 0.70 | HTR6 (0.45) | HTR6HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101263136-A | Benzimidazole derivatives as 5-HT6, 5-HT24 | HOFFMANN LA ROCHE (CH) | 2008-09-10 | — | — | CN | disclosed |