Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.53 |
| ▸ | PDCD1LG2 | Q9BQ51 | 10/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776816 | 1.00 | CD274 (0.53) | CD274PDCD1LG2KCNA5PDCD1 | |
| SCHEMBL23198417 | 0.85 | CD274 (0.54) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24722594 | 0.85 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL19597235 | 0.82 | DPP7 (0.40) | CD274PDCD1LG2 | |
| SCHEMBL24345978 | 0.82 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL1776611 | 0.79 | CRBN (0.47) | CD274PDCD1LG2KCNA5 | |
| SCHEMBL31145840 | 0.73 | CD274 (0.58) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23726237 | 0.73 | PDCD1LG2 (0.63) | CD274PDCD1LG2 | |
| SCHEMBL1776764 | 0.72 | CNR1 (0.41) | CD274PDCD1LG2KCNA5 | |
| SCHEMBL30431831 | 0.72 | CD274 (0.48) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | claimed |
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | disclosed |