Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.58 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.58 |
| ▸ | PDCD1 | Q15116 | 15/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22675478 | 0.86 | CD274 (0.56) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21507062 | 0.73 | CD274 (1.00) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24722594 | 0.73 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL1776816 | 0.73 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23198417 | 0.73 | CD274 (0.54) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27717312 | 0.73 | CD274 (0.53) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27080569 | 0.72 | CD274 (0.63) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27080574 | 0.72 | CD274 (0.63) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL2644039 | 0.72 | VNN1 (0.53) | VNN1 | |
| SCHEMBL22675492 | 0.71 | IRAK4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688777-A1 | NOVEL PD-L1 INHIBITORS | Affirma Biotech S. L. (ES) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024200308-A1 | NOVEL PD-L1 INHIBITORS | Affirma Biotech S. L. (ES) | 2024-10-03 | — | — | WO | disclosed |