Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 5/20 | 0.54 |
| ▸ | RXRB | P28702 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701985 | 0.82 | SLC6A2 (0.47) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14289858 | 0.82 | SLC6A2 (0.47) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| Benzoic Acid SCHEMBL4532566 | 0.81 | NR4A2 (0.54) | NR4A1NR4A2NR4A3RXRARXRB | |
| SCHEMBL6576561 | 0.81 | NR4A2 (0.54) | NR4A1NR4A2NR4A3RXRARXRB | |
| SCHEMBL1842790 | 0.80 | RXRA (0.47) | RXRARXRBSRD5A2PLA2G4BKMT2A | |
| SCHEMBL14966727 | 0.78 | MAPK1 (0.47) | RXRARXRBSRD5A2RXRGKMT2A | |
| SCHEMBL3313827 | 0.78 | RXRA (0.57) | NR4A1NR4A2NR4A3RXRARXRB | |
| SCHEMBL1749896 | 0.77 | TP53 (0.46) | RXRARXRBPLA2G4BKMT2A | |
| SCHEMBL23214448 | 0.77 | PTGER4 (0.69) | NR4A1NR4A2NR4A3RXRARXRB | |
| SCHEMBL23214450 | 0.77 | PTGER4 (0.69) | NR4A1NR4A2NR4A3RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998432-A | Bicyclic compounds | TAKEDA PHARMACEUTICAL | 2014-08-20 | — | — | CN | disclosed |
| CN-101146766-A | Acyl hydrazides as kinase inhibitors, in particular for SGK | MERCK PATENT GMBH (DE) | 2008-03-19 | — | — | CN | disclosed |