Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.47 |
| ▸ | RXRB | P28702 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586340 | 0.88 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL6573433 | 0.88 | SLC1A3 (0.45) | NR4A2NR4A1NR4A3SRD5A2SLC1A3 | |
| SCHEMBL9292657 | 0.84 | CNR1 (0.48) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL9291604 | 0.84 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL6572713 | 0.83 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL10584101 | 0.83 | NR4A1 (0.57) | NR4A2NR4A1NR4A3SRD5A2CYP1A2 | |
| SCHEMBL5122883 | 0.81 | CNR2 (0.54) | MEN1KMT2ATSHR | |
| SCHEMBL27717399 | 0.81 | NR4A1 (0.54) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL27297614 | 0.79 | SLC1A2 (0.61) | NR4A2NR4A1NR4A3SRD5A2PLA2G4B | |
| SCHEMBL9475960 | 0.77 | ALDH1A1 (0.56) | NR4A2NR4A1NR4A3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973537-A4 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DRUGABUSE SCIENCES S A S (FR) | 2004-12-01 | — | — | EP | disclosed |
| US-6541004-B1 | Cocaethylene immunogens and antibodies | DRUGABUSE SCIENCES, INC. | 2003-04-01 | — | — | US | disclosed |
| US-20020102659-A1 | Cocaethylene immunogens and antibodies | DRUGABUSE SCIENCES S.A.S. (FR) | 2002-08-01 | — | — | US | disclosed |
| US-6114508-A | 2-CARBOXYETHYL-3-BENZOYLOXY-N-METHYLTROPANE DERIVATIVES; COCAINE DETOXIFICATION; VACCINES | DRUGABUSE SCIENCES, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0973537-A1 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DrugAbuse Sciences S.A.S. (FR) | 2000-01-26 | — | — | EP | disclosed |
| US-5817770-A | N-METHYLTROPANE, 2-CARBOXYETHYL- OR N-ETHYLCARBOXAMIDE, 3-BENZOYLOXY- OR BENZAMIDO- | DRUG ABUSE SCIENCES, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1998042359-A1 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DRUG ABUSE SCIENCES, INC. (US) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102659-A1 | Cocaethylene immunogens and antibodies | CES2, BCHE, ERP44 | NR4A2 1992/4885NR4A1 1974/4885NR4A3 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.