Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541520 | 0.76 | HTR2C (0.41) | HTR6HTR2C | |
| SCHEMBL28131823 | 0.72 | HTR6 (0.38) | HTR6 | |
| SCHEMBL4623351 | 0.68 | HTR2C (0.51) | HTR6HTR2C | |
| SCHEMBL29764435 | 0.68 | HTR2C (0.51) | HTR6HTR2C | |
| Hydrochloric Acid SCHEMBL21381710 | 0.68 | HTR2C (0.50) | HTR6HTR2C | |
| SCHEMBL27905525 | 0.65 | HRH3 (0.35) | — | |
| SCHEMBL29764357 | 0.65 | HTR6 (0.46) | HTR6 | |
| SCHEMBL25215103 | 0.64 | CA12 (0.36) | — | |
| SCHEMBL2522630 | 0.64 | HTR2C (0.46) | HTR6HTR2C | |
| SCHEMBL9827832 | 0.64 | SLC18A3 (0.52) | HTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101291925-A | Piperidin-4-yl-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2008-10-22 | — | — | CN | disclosed |