Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905525 | 0.93 | HRH3 (0.35) | HRH3 | |
| SCHEMBL30769910 | 0.78 | TLR9 (0.43) | HTR6ROCK1MKNK1MKNK2HTR1A | |
| SCHEMBL2244757 | 0.78 | TLR9 (0.43) | HTR6ROCK1MKNK1MKNK2HTR1A | |
| Hydrochloric Acid SCHEMBL27035336 | 0.76 | HTR2C (0.42) | HTR6ROCK1MKNK1MKNK2HTR1A | |
| SCHEMBL27965089 | 0.73 | PARP1 (0.42) | HTR6ROCK1MKNK1MKNK2HTR1A | |
| SCHEMBL21311738 | 0.72 | HRH3 (0.35) | ROCK1MKNK1MKNK2HRH3 | |
| SCHEMBL8562692 | 0.72 | HTT (0.40) | HTR6ROCK1MKNK1MKNK2HTR1A | |
| SCHEMBL27717746 | 0.72 | HTR6 (0.36) | HTR6 | |
| SCHEMBL1429509 | 0.71 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL27035428 | 0.70 | HRH4 (0.41) | HTR6ROCK1HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109966294-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109897038-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-106008466-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-106397418-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE公司 | 2017-02-15 | — | — | CN | disclosed |