Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426631 | 1.00 | ALDH1A1 (0.44) | ALDH1A1POLBHTR2AHTR2CMAOB | |
| SCHEMBL27738940 | 0.88 | PTGES2 (0.50) | MAOBKMT2APTGES2MEN1 | |
| SCHEMBL5414811 | 0.88 | PTGES2 (0.50) | MAOBKMT2APTGES2MEN1 | |
| SCHEMBL5418978 | 0.86 | HTR2A (0.43) | ALDH1A1POLBHTR2AHTR2CMAOB | |
| SCHEMBL27717765 | 0.86 | HTR2A (0.43) | ALDH1A1POLBHTR2AHTR2CMAOB | |
| SCHEMBL27717775 | 0.86 | PTGES2 (0.48) | HTR2AHTR2CMAOBPTGES2 | |
| SCHEMBL5414820 | 0.86 | PTGES2 (0.48) | HTR2AHTR2CMAOBPTGES2 | |
| SCHEMBL5415170 | 0.85 | GPR27 (0.41) | ALDH1A1POLBMAOBKMT2APKM | |
| SCHEMBL27738925 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1POLBKMT2APTPN1LMNA | |
| SCHEMBL5416951 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1POLBKMT2APTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268042-A | Styryl sulfonamides, their preparation and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | claimed |
| CN-101268042-A | Styryl sulfonamides, their preparation and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |