Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620479 | 0.87 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL28276065 | 0.86 | KMT2A (0.50) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL28311549 | 0.84 | KMT2A (0.49) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL7592440 | 0.81 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL28059209 | 0.81 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL27995293 | 0.81 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL27601968 | 0.80 | F7 (0.53) | L3MBTL1ALDH1A1LMNAKMT2AF7 | |
| SCHEMBL27851778 | 0.80 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| Ethyl Nicotinate SCHEMBL30545166 | 0.79 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL811679 | 0.79 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1LMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101289421-A | Method for synthesizing nicotinyl amino acids and sensitizing effect thereof to tumor radiotherapy | RADIOLOGY RES INST CHINESE ACA (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-101289421-A | Method for synthesizing nicotinyl amino acids and sensitizing effect thereof to tumor radiotherapy | RADIOLOGY RES INST CHINESE ACA (CN) | 2008-10-22 | — | — | CN | disclosed |